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DIPG-37. THE KETONE BODY β-HYDROXYBUTYRATE ACTS AS AN EPIGENETIC MODIFIER AND INCREASES RADIATION-INDUCED DNA DAMAGE IN DIFFUSE INTRINSIC PONTINE GLIOMA
Diffuse Intrinsic Pontine Glioma (DIPG) is a highly infiltrative pediatric tumor with a median survival of approximately 9 months. Due to its location, the tumor is generally considered inoperable and there are few therapeutic options. Radiation is the only primary treatment for these tumors; howeve...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477371/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.058 |
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