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DIPG-08. THE ROLE OF KMT5B/C AND H4K20 DI/TRIMETHYLATION IN DIPG
Diffuse intrinsic pontine glioma (DIPG) are incurable childhood brain tumours marked by alterations in histone 3 in the form of somatic K27M mutations and loss of H3K27 trimethylation (H3K27me3). These highly aggressive tumours display extensive intratumoral heterogeneity, despite their relatively m...
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| Izdano u: | Neuro Oncol |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477248/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.029 |
| Oznake: |
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