ATRT-08. SMARCB1 LOSS INTERACTS WITH NEURAL DIFFERENTIATION STATE TO GENERATE CELL TYPE-SPECIFIC PHENOTYPES

Atypical teratoid rhabdoid tumors (ATRT) are challenging pediatric brain tumors which are predominantly associated with inactivation of the gene SMARCB1. As SMARCB1 is a conserved subunit of the chromatin remodeling BAF complex, we hypothesize that the effect of its loss of function is influenced by...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Parisian, Alison, Koga, Tomoyuki, Furnari, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Atypical Teratoid Rhabdoid Tumor (ATRT)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477220/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.007
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