Novel 3,4-Dihydroisocoumarins Inhibit Human P-gp and BCRP in Multidrug Resistant Tumors and Demonstrate Substrate Inhibition of Yeast Pdr5

Multidrug resistance (MDR) in tumors and pathogens remains a major problem in the efficacious treatment of patients by reduction of therapy options and subsequent treatment failure. Various mechanisms are described to be involved in the development of MDR with overexpression of ATP-binding cassette...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Sachs, Julia, Döhl, Katja, Weber, Anja, Bonus, Michele, Ehlers, Ferdinand, Fleischer, Edmond, Klinger, Anette, Gohlke, Holger, Pietruszka, Jörg, Schmitt, Lutz, Teusch, Nicole
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476959/
https://ncbi.nlm.nih.gov/pubmed/31040786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00400
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares