Arsenite malignantly transforms human prostate epithelial cells in vitro by gene amplification of mutated KRAS

Inorganic arsenic is an environmental human carcinogen of several organs including the urinary tract. RWPE-1 cells are immortalized, non-tumorigenic, human prostate epithelia that become malignantly transformed into the CAsE-PE line after continuous in vitro exposure to 5μM arsenite over a period of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Merrick, B. Alex, Phadke, Dhiral P., Bostrom, Meredith A., Shah, Ruchir R., Wright, Garron M., Wang, Xinguo, Gordon, Oksana, Pelch, Katherine E., Auerbach, Scott S., Paules, Richard S., DeVito, Michael J., Waalkes, Michael P., Tokar, Erik J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2019
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476498/
https://ncbi.nlm.nih.gov/pubmed/31009485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215504
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