KRAS-retroviral fusion transcripts and gene amplification in arsenic-transformed, human prostate CAsE-PE cancer cells

CAsE-PE cells are an arsenic-transformed, human prostate epithelial line containing oncogenic mutations in KRAS compared to immortalized, normal KRAS parent cells, RWPE-1. We previously reported increased copy number mutated KRAS in CAsE-PE cells, suggesting gene amplification. Here, KRAS flanking g...

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Publicat a:Toxicol Appl Pharmacol
Autors principals: Merrick, B. Alex, Phadke, Dhiral P., Bostrom, Meredith A., Shah, Ruchir R., Wright, Garron M., Wang, Xinguo, Gordon, Oksana, Pelch, Katherine E., Auerbach, Scott S., Paules, Richard S., DeVito, Michael J., Waalkes, Michael P., Tokar, Erik J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606314/
https://ncbi.nlm.nih.gov/pubmed/32344290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115017
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