KRAS-retroviral fusion transcripts and gene amplification in arsenic-transformed, human prostate CAsE-PE cancer cells

CAsE-PE cells are an arsenic-transformed, human prostate epithelial line containing oncogenic mutations in KRAS compared to immortalized, normal KRAS parent cells, RWPE-1. We previously reported increased copy number mutated KRAS in CAsE-PE cells, suggesting gene amplification. Here, KRAS flanking g...

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Detaylı Bibliyografya
Yayımlandı:Toxicol Appl Pharmacol
Asıl Yazarlar: Merrick, B. Alex, Phadke, Dhiral P., Bostrom, Meredith A., Shah, Ruchir R., Wright, Garron M., Wang, Xinguo, Gordon, Oksana, Pelch, Katherine E., Auerbach, Scott S., Paules, Richard S., DeVito, Michael J., Waalkes, Michael P., Tokar, Erik J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606314/
https://ncbi.nlm.nih.gov/pubmed/32344290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115017
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