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Silencing KRAS Overexpression in Cadmium-Transformed Prostate Epithelial Cells Mitigates Malignant Phenotype

Cadmium (Cd) is a potential human prostate carcinogen. Chronic Cd exposure malignantly transforms RWPE-1 human prostate epithelial cells into CTPE cells by an unclear mechanism. Previous studies show that RWPE-1 can also be malignantly transformed by arsenic, and KRAS activation is key to causation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Res Toxicol
Egile Nagusiak: Ngalame, Ntube N.O., Waalkes, Michael P., Tokar, Erik J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576187/
https://ncbi.nlm.nih.gov/pubmed/27510461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00137
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