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Mitigation of arsenic-induced acquired cancer phenotype in prostate cancer stem cells by miR-143 restoration

Inorganic arsenic, an environmental contaminant and a human carcinogen is associated with prostate cancer. Emerging evidence suggests cancer stem cells (CSCs) are the driving force of carcinogenesis. Chronic arsenic exposure malignantly transforms the human normal prostate stem/progenitor cell (SC)...

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Publicat a:Toxicol Appl Pharmacol
Autors principals: Ngalame, Ntube N. O., Makia, Ngome L., Waalkes, Michael P., Tokar, Erik J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917483/
https://ncbi.nlm.nih.gov/pubmed/26721309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.12.013
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