Aberrant microRNA Expression Likely Controls RAS Oncogene Activation During Malignant Transformation of Human Prostate Epithelial and Stem Cells by Arsenic

Inorganic arsenic (iAs), a human carcinogen, potentially targets the prostate. iAs malignantly transforms the RWPE-1 human prostate epithelial line to CAsE-PE cells, and a derivative normal stem cell (SC) line, WPE-stem, to As-Cancer SC (As-CSC) line. MicroRNAs (miRNA) are noncoding but exert negati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ngalame, Ntube N. O., Tokar, Erik J., Person, Rachel J., Xu, Yuanyuan, Waalkes, Michael P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Carcinogenicity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968309/
https://ncbi.nlm.nih.gov/pubmed/24431212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu002
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