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Recruitment of Normal Stem Cells to an Oncogenic Phenotype by Noncontiguous Carcinogen-Transformed Epithelia Depends on the Transforming Carcinogen

Background: Cancer stem cells (CSCs) drive tumor initiation, progression, and metastasis. The microenvironment is critical to the fate of CSCs. We have found that a normal stem cell (NSC) line from human prostate (WPE-stem) is recruited into CSC-like cells by nearby, but noncontiguous, arsenic-trans...

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Bibliografiset tiedot
Päätekijät: Xu, Yuanyuan, Tokar, Erik J., Person, Rachel J., Orihuela, Ruben G., Ngalame, Ntube N.O., Waalkes, Michael P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Institute of Environmental Health Sciences 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734505/
https://ncbi.nlm.nih.gov/pubmed/23687063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1306714
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