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Overabundance of Putative Cancer Stem Cells in Human Skin Keratinocyte Cells Malignantly Transformed by Arsenic

Arsenic is a human skin carcinogen. Cancer is probably a disease driven by stem cells (SCs), and SCs are likely a key target during arsenic oncogenesis. In utero arsenic exposure predisposes mice to skin cancers that overproduce cancer SCs (CSCs) and have distorted CSC signaling and population dynam...

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Detalhes bibliográficos
Main Authors: Sun, Yang, Tokar, Erik J., Waalkes, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243751/
https://ncbi.nlm.nih.gov/pubmed/22011395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr282
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