Validation of Plasmodium falciparum deoxyhypusine synthase as an antimalarial target

BACKGROUND: Hypusination is an essential post-translational modification in eukaryotes. The two enzymes required for this modification, namely deoxyhypusine synthase (DHS) and deoxyhypusine hydrolase are also conserved. Plasmodium falciparum human malaria parasites possess genes for both hypusinatio...

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Detaylı Bibliyografya
Yayımlandı:PeerJ
Asıl Yazarlar: Aroonsri, Aiyada, Posayapisit, Navaporn, Kongsee, Jindaporn, Siripan, Onsiri, Vitsupakorn, Danoo, Utaida, Sugunya, Uthaipibull, Chairat, Kamchonwongpaisan, Sumalee, Shaw, Philip J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: PeerJ Inc. 2019
Konular:
Biochemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475138/
https://ncbi.nlm.nih.gov/pubmed/31024761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.6713
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