Validation of Plasmodium falciparum deoxyhypusine synthase as an antimalarial target

BACKGROUND: Hypusination is an essential post-translational modification in eukaryotes. The two enzymes required for this modification, namely deoxyhypusine synthase (DHS) and deoxyhypusine hydrolase are also conserved. Plasmodium falciparum human malaria parasites possess genes for both hypusinatio...

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Detalles Bibliográficos
Publicado en:PeerJ
Main Authors: Aroonsri, Aiyada, Posayapisit, Navaporn, Kongsee, Jindaporn, Siripan, Onsiri, Vitsupakorn, Danoo, Utaida, Sugunya, Uthaipibull, Chairat, Kamchonwongpaisan, Sumalee, Shaw, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado: PeerJ Inc. 2019
Assuntos:
Biochemistry
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475138/
https://ncbi.nlm.nih.gov/pubmed/31024761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.6713
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