Caricamento...

Esterification Delivers a Functional Enzyme into a Human Cell

A major hurdle in chemical biology is the delivery of native proteins into the cytosol of mammalian cells. Herein, we report that esterification of the carboxyl groups of an enzyme with a diazo compound enables not only its passage into the cytosol, but also the retention of its catalytic activity t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:ACS Chem Biol
Autori principali: Ressler, Valerie T., Mix, Kalie A., Raines, Ronald T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474803/
https://ncbi.nlm.nih.gov/pubmed/30830748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00033
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !