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Cytosolic Delivery of Proteins by Bioreversible Esterification

Cloaking its carboxyl groups with a hydrophobic moiety is shown to enable a protein to enter the cytosol of a mammalian cell. Diazo compounds derived from (p-methylphenyl)glycine were screened for the ability to esterify the green fluorescent protein (GFP) in an aqueous environment. Esterification o...

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Detaylı Bibliyografya
Yayımlandı:J Am Chem Soc
Asıl Yazarlar: Mix, Kalie A., Lomax, Jo E., Raines, Ronald T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856659/
https://ncbi.nlm.nih.gov/pubmed/28976737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b06597
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