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Cytosolic Delivery of Proteins by Bioreversible Esterification
Cloaking its carboxyl groups with a hydrophobic moiety is shown to enable a protein to enter the cytosol of a mammalian cell. Diazo compounds derived from (p-methylphenyl)glycine were screened for the ability to esterify the green fluorescent protein (GFP) in an aqueous environment. Esterification o...
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| Publicat a: | J Am Chem Soc |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856659/ https://ncbi.nlm.nih.gov/pubmed/28976737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b06597 |
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