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Site-Specific Antibody Functionalization Using Tetrazine–Styrene Cycloaddition

Biologics, such as antibody–drug conjugates, are becoming mainstream therapeutics. Consequently, methods to functionalize biologics without disrupting their native properties are essential for identifying, characterizing, and translating candidate biologics from the bench to clinical practice. Here,...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Umlauf, Benjamin J., Mix, Kalie A., Grosskopf, Vanessa A., Raines, Ronald T., Shusta, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963889/
https://ncbi.nlm.nih.gov/pubmed/29694034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00114
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