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Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor
Angiogenin (ANG) is a secretory ribonuclease that promotes the proliferation of endothelial cells, leading to angiogenesis. This function relies on its ribonucleolytic activity, which is low for simple RNA substrates. Upon entry into the cytosol, ANG is sequestered by the ribonuclease inhibitor prot...
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| Publicado no: | RNA |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6049508/ https://ncbi.nlm.nih.gov/pubmed/29748193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.065516.117 |
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