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A Boronic Acid Conjugate of Angiogenin that Shows ROS-Responsive Neuroprotective Activity
Angiogenin (ANG) is a human ribonuclease that is compromised in patients with amyotrophic lateral sclerosis (ALS). ANG also promotes neovascularization, and can induce hemorrhage and encourage tumor growth. The causal neurodegeneration of ALS is associated with reactive oxygen species, which are als...
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| Publicado en: | Angew Chem Int Ed Engl |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5418131/ https://ncbi.nlm.nih.gov/pubmed/28120377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611446 |
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