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Genetic selection for peptide inhibitors of angiogenin

The improper regulation of angiogenesis is implicit in a variety of diseases, including cancer. Angiogenin is unique among angiogenic factors in its having ribonucleolytic activity. Inhibitors of this activity could serve as chemotherapeutics. The ribonucleolytic activity of angiogenin is toxic to t...

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Detalhes bibliográficos
Main Authors: Smith, Bryan D., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587640/
https://ncbi.nlm.nih.gov/pubmed/18308863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzm089
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