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Genetic selection for peptide inhibitors of angiogenin

The improper regulation of angiogenesis is implicit in a variety of diseases, including cancer. Angiogenin is unique among angiogenic factors in its having ribonucleolytic activity. Inhibitors of this activity could serve as chemotherapeutics. The ribonucleolytic activity of angiogenin is toxic to t...

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Bibliografiske detaljer
Main Authors: Smith, Bryan D., Raines, Ronald T.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587640/
https://ncbi.nlm.nih.gov/pubmed/18308863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzm089
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