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Genetic selection for peptide inhibitors of angiogenin

The improper regulation of angiogenesis is implicit in a variety of diseases, including cancer. Angiogenin is unique among angiogenic factors in its having ribonucleolytic activity. Inhibitors of this activity could serve as chemotherapeutics. The ribonucleolytic activity of angiogenin is toxic to t...

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Bibliografski detalji
Glavni autori: Smith, Bryan D., Raines, Ronald T.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587640/
https://ncbi.nlm.nih.gov/pubmed/18308863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzm089
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