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Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor
Angiogenin (ANG) is a secretory ribonuclease that promotes the proliferation of endothelial cells, leading to angiogenesis. This function relies on its ribonucleolytic activity, which is low for simple RNA substrates. Upon entry into the cytosol, ANG is sequestered by the ribonuclease inhibitor prot...
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| 出版年: | RNA |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6049508/ https://ncbi.nlm.nih.gov/pubmed/29748193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.065516.117 |
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