Human retinoic acid-regulated CD161(+) regulatory T cells support wound repair in intestinal mucosa

Repair of tissue damaged during inflammatory processes is key to return of local homeostasis and restoration of epithelial integrity. Here we describe CD161(+) regulatory T cells (T(reg) cells) as a distinct, highly suppressive, population of T(regs) mediating wound-healing. These T(regs) were enric...

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Udgivet i:Nat Immunol
Main Authors: Povoleri, Giovanni AM, Nova-Lamperti, Estefania, Scottà, Cristiano, Fanelli, Giorgia, Chen, Yun-Ching, Becker, Pablo, Boardman, Dominic, Costantini, Benedetta, Romano, Marco, Pavlidis, Polychronis, McGregor, Reuben, Pantazi, Eirini, Chauss, Daniel, Sun, Hong-Wei, Shih, Han-Yu, Cousins, David, Cooper, Nichola, Powell, Nick, Kemper, Claudia, Pirooznia, Mehdi, Laurence, Arian, Kordasti, Shahram, Kazemian, Majid, Lombardi, Giovanna, Afzali, Behdad
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474659/
https://ncbi.nlm.nih.gov/pubmed/30397350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0230-z
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