SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyperactivation

Patients with coronavirus disease 2019 (COVID-19) present with a range of devastating acute clinical manifestations affecting the lungs, liver, kidneys and gut. The best-characterized entry receptor for the disease-causing virus SARS-CoV2, angiotensin converting enzyme (ACE) 2, is highly expressed i...

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Publicat a:Res Sq
Autors principals: Yan, Bingyu, Freiwald, Tilo, Chauss, Daniel, Wang, Luopin, West, Erin, Bibby, Jack, Olson, Matthew, Kordasti, Shahram, Portilla, Didier, Laurence, Arian, Lionakis, Michail S, Kemper, Claudia, Afzali, Behdad, Kazemian, Majid
Format: Artigo
Idioma:Inglês
Publicat: American Journal Experts 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336704/
https://ncbi.nlm.nih.gov/pubmed/32702726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21203/rs.3.rs-33390/v1
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