CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner

Treg cells are critical for the prevention of autoimmune diseases and are thus prime candidates for cell-based clinical therapy. However, human Treg cells are “plastic”, and are able to produce IL-17 under inflammatory conditions. Here, we identify and characterize the human Treg subpopulation that...

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Bibliografiset tiedot
Päätekijät: Afzali, Behdad, Mitchell, Peter J, Edozie, Francis C, Povoleri, Giovanni AM, Dowson, Sophie E, Demandt, Laura, Walter, Gina, Canavan, James B, Scotta, Cristiano, Menon, Bina, Chana, Prabhjoat S, Khamri, Wafa, Kordasti, Shahram Y, Heck, Susanne, Grimbacher, Bodo, Tree, Timothy, Cope, Andrew P, Taams, Leonie S, Lechler, Robert I, John, Susan, Lombardi, Giovanna
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2013
Aiheet:
Cellular Immune Response
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815561/
https://ncbi.nlm.nih.gov/pubmed/23677517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243296
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