CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner

Treg cells are critical for the prevention of autoimmune diseases and are thus prime candidates for cell-based clinical therapy. However, human Treg cells are “plastic”, and are able to produce IL-17 under inflammatory conditions. Here, we identify and characterize the human Treg subpopulation that...

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Main Authors: Afzali, Behdad, Mitchell, Peter J, Edozie, Francis C, Povoleri, Giovanni AM, Dowson, Sophie E, Demandt, Laura, Walter, Gina, Canavan, James B, Scotta, Cristiano, Menon, Bina, Chana, Prabhjoat S, Khamri, Wafa, Kordasti, Shahram Y, Heck, Susanne, Grimbacher, Bodo, Tree, Timothy, Cope, Andrew P, Taams, Leonie S, Lechler, Robert I, John, Susan, Lombardi, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
Assuntos:
Cellular Immune Response
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815561/
https://ncbi.nlm.nih.gov/pubmed/23677517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243296
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