CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner

Treg cells are critical for the prevention of autoimmune diseases and are thus prime candidates for cell-based clinical therapy. However, human Treg cells are “plastic”, and are able to produce IL-17 under inflammatory conditions. Here, we identify and characterize the human Treg subpopulation that...

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Библиографические подробности
Главные авторы: Afzali, Behdad, Mitchell, Peter J, Edozie, Francis C, Povoleri, Giovanni AM, Dowson, Sophie E, Demandt, Laura, Walter, Gina, Canavan, James B, Scotta, Cristiano, Menon, Bina, Chana, Prabhjoat S, Khamri, Wafa, Kordasti, Shahram Y, Heck, Susanne, Grimbacher, Bodo, Tree, Timothy, Cope, Andrew P, Taams, Leonie S, Lechler, Robert I, John, Susan, Lombardi, Giovanna
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2013
Предметы:
Cellular Immune Response
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815561/
https://ncbi.nlm.nih.gov/pubmed/23677517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243296
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