PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation

The signaling events involved in the onset of ovarian cancer from the fallopian tube epithelium (FTE) are crucial for early detection and treatment of the disease, but they remain poorly defined. Conditional homozygous knockout of PTEN mediated by PAX8-cre recombinase was sufficient to drive endomet...

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Библиографические подробности
Опубликовано в: :Oncogene
Главные авторы: Russo, Angela, Czarnecki, Austin A., Dean, Matthew, Modi, Dimple A., Lantvit, Daniel D., Hardy, Laura, Baligod, Seth, Davis, David A., Wei, Jian-Jun, Burdette, Joanna E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472269/
https://ncbi.nlm.nih.gov/pubmed/29367766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0097-8
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