PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation

The signaling events involved in the onset of ovarian cancer from the fallopian tube epithelium (FTE) are crucial for early detection and treatment of the disease, but they remain poorly defined. Conditional homozygous knockout of PTEN mediated by PAX8-cre recombinase was sufficient to drive endomet...

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Bibliografische gegevens
Gepubliceerd in:Oncogene
Hoofdauteurs: Russo, Angela, Czarnecki, Austin A., Dean, Matthew, Modi, Dimple A., Lantvit, Daniel D., Hardy, Laura, Baligod, Seth, Davis, David A., Wei, Jian-Jun, Burdette, Joanna E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472269/
https://ncbi.nlm.nih.gov/pubmed/29367766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0097-8
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