Silencing PTEN in the fallopian tube promotes enrichment of cancer stem cell-like function through loss of PAX2

High-grade serous ovarian cancer (HGSOC) is the most lethal gynecological malignancy that is primarily detected at the metastatic stage. Most HGSOC originates from the fallopian tube epithelium (FTE) and metastasizes to the ovary before invading the peritoneum; therefore, it is crucial to study dise...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Russo, Angela, Colina, Jose A., Moy, Junlone, Baligod, Seth, Czarnecki, Austin A., Varughese, Peter, Lantvit, Daniel D., Dean, Matthew J., Burdette, Joanna E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027874/
https://ncbi.nlm.nih.gov/pubmed/33828085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03663-2
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