Loss of PTEN in Fallopian Tube Epithelium Results in Multicellular Tumor Spheroid Formation and Metastasis to the Ovary

High-grade serous ovarian cancer (HGSOC) can originate in the fallopian tube and then spread to the ovary. Our objective was to evaluate the role of multicellular tumor spheroids (MTS) in ovarian metastasis. By testing a panel of murine oviductal epithelial (MOE) cells with genetic alterations mimic...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Dean, Matthew, Jin, Vivian, Bergsten, Tova M., Austin, Julia R., Lantvit, Daniel D., Russo, Angela, Burdette, Joanna E.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627669/
https://ncbi.nlm.nih.gov/pubmed/31242614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060884
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