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Loss of PTEN in Fallopian Tube Epithelium Results in Multicellular Tumor Spheroid Formation and Metastasis to the Ovary

High-grade serous ovarian cancer (HGSOC) can originate in the fallopian tube and then spread to the ovary. Our objective was to evaluate the role of multicellular tumor spheroids (MTS) in ovarian metastasis. By testing a panel of murine oviductal epithelial (MOE) cells with genetic alterations mimic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancers (Basel)
Egile Nagusiak: Dean, Matthew, Jin, Vivian, Bergsten, Tova M., Austin, Julia R., Lantvit, Daniel D., Russo, Angela, Burdette, Joanna E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627669/
https://ncbi.nlm.nih.gov/pubmed/31242614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060884
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