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Loss of PTEN in Fallopian Tube Epithelium Results in Multicellular Tumor Spheroid Formation and Metastasis to the Ovary

High-grade serous ovarian cancer (HGSOC) can originate in the fallopian tube and then spread to the ovary. Our objective was to evaluate the role of multicellular tumor spheroids (MTS) in ovarian metastasis. By testing a panel of murine oviductal epithelial (MOE) cells with genetic alterations mimic...

詳細記述

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Dean, Matthew, Jin, Vivian, Bergsten, Tova M., Austin, Julia R., Lantvit, Daniel D., Russo, Angela, Burdette, Joanna E.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627669/
https://ncbi.nlm.nih.gov/pubmed/31242614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060884
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