PAX2 Function, Regulation and Targeting in Fallopian Tube-Derived High Grade Serous Ovarian Cancer

The fallopian tube epithelium (FTE) is one of the progenitor populations for high-grade serous ovarian cancer (HGSC). Loss of PAX2 is the earliest known molecular aberration in the FTE occurring in serous carcinogenesis followed by a mutation in p53. Pathological studies report consistent loss of PA...

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Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Modi, Dimple A., Tagare, Rosemarie D., Karthikeyan, Subbulakshmi, Russo, Angela, Dean, Matthew, Davis, David A., Lantvit, Daniel D., Burdette, Joanna E.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581540/
https://ncbi.nlm.nih.gov/pubmed/27991925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.455
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