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Activin A Stimulates Migration of the Fallopian Tube Epithelium, an Origin of High-Grade Serous Ovarian Cancer, through Non-Canonical Signaling

Factors that stimulate the migration of fallopian tube epithelial (FTE)-derived high-grade serous ovarian cancer (HGSOC) to the ovary are poorly elucidated. This study characterized the effect of the ovarian hormone, activin A, on normal FTE and HGSOC. Activin A and TGFβ1 induced an epithelial-to-me...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Dean, Matthew, Davis, David A., Burdette, Joanna E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336484/
https://ncbi.nlm.nih.gov/pubmed/28115208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.01.011
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