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Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma

The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial, with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered candidates. Here, by using genetically engineered mouse models and organoids, we assessed the tumor-forming properties of...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Zhang, Shuang, Dolgalev, Igor, Zhang, Tao, Ran, Hao, Levine, Douglas A., Neel, Benjamin G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879755/
https://ncbi.nlm.nih.gov/pubmed/31772167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13116-2
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