Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma

The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial, with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered candidates. Here, by using genetically engineered mouse models and organoids, we assessed the tumor-forming properties of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Zhang, Shuang, Dolgalev, Igor, Zhang, Tao, Ran, Hao, Levine, Douglas A., Neel, Benjamin G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879755/
https://ncbi.nlm.nih.gov/pubmed/31772167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13116-2
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