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The Less the Better: How Suppressed Base Addition Boosts Production of Monoclonal Antibodies With Chinese Hamster Ovary Cells

Biopharmaceutical production processes strive for the optimization of economic efficiency. Among others, the maximization of volumetric productivity is a key criterion. Typical parameters such as partial pressure of CO(2) (pCO(2)) and pH are known to influence the performance although reasons are no...

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Foilsithe in:Front Bioeng Biotechnol
Main Authors: Becker, Max, Junghans, Lisa, Teleki, Attila, Bechmann, Jan, Takors, Ralf
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470187/
https://ncbi.nlm.nih.gov/pubmed/31032253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00076
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