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The Less the Better: How Suppressed Base Addition Boosts Production of Monoclonal Antibodies With Chinese Hamster Ovary Cells

Biopharmaceutical production processes strive for the optimization of economic efficiency. Among others, the maximization of volumetric productivity is a key criterion. Typical parameters such as partial pressure of CO(2) (pCO(2)) and pH are known to influence the performance although reasons are no...

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Podrobná bibliografie
Vydáno v:Front Bioeng Biotechnol
Hlavní autoři: Becker, Max, Junghans, Lisa, Teleki, Attila, Bechmann, Jan, Takors, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470187/
https://ncbi.nlm.nih.gov/pubmed/31032253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00076
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