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Serum-Free Medium for Recombinant Protein Expression in Chinese Hamster Ovary Cells

At present, nearly 70% of recombinant therapeutic proteins (RTPs) are produced by Chinese hamster ovary (CHO) cells, and serum-free medium (SFM) is necessary for their culture to produce RTPs. In this review, the history and key components of SFM are first summarized, and its preparation and experim...

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Библиографические подробности
Опубликовано в: :Front Bioeng Biotechnol
Главные авторы: Li, Weifeng, Fan, Zhenlin, Lin, Yan, Wang, Tian-Yun
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006267/
https://ncbi.nlm.nih.gov/pubmed/33791287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.646363
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