Enhanced recombinant factor VII expression in Chinese hamster ovary cells by optimizing signal peptides and fed-batch medium

Signal peptides play an important role in directing and efficiently transporting secretory proteins to their proper locations in the endoplasmic reticulum of mammalian cells. The aim of this study was to enhance the expression of recombinant coagulation factor VII (rFVII) in CHO cells by optimizing...

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Detalhes bibliográficos
Publicado no:Bioengineered
Main Authors: Peng, Lin, Yu, Xiao, Li, Chengyuan, Cai, Yanfei, Chen, Yun, He, Yang, Yang, Jianfeng, Jin, Jian, Li, Huazhong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927201/
https://ncbi.nlm.nih.gov/pubmed/27116572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1176656
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