Enhanced recombinant factor VII expression in Chinese hamster ovary cells by optimizing signal peptides and fed-batch medium

Signal peptides play an important role in directing and efficiently transporting secretory proteins to their proper locations in the endoplasmic reticulum of mammalian cells. The aim of this study was to enhance the expression of recombinant coagulation factor VII (rFVII) in CHO cells by optimizing...

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Vydáno v:Bioengineered
Hlavní autoři: Peng, Lin, Yu, Xiao, Li, Chengyuan, Cai, Yanfei, Chen, Yun, He, Yang, Yang, Jianfeng, Jin, Jian, Li, Huazhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927201/
https://ncbi.nlm.nih.gov/pubmed/27116572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1176656
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