Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport

The p38 signal transduction pathway can be activated transiently or constitutively, depending on the contexts in which the activation occurs. However, the biological consequence of constitutive activation of p38 is largely unknown. After screening 300 transcriptional cofactors, we identified CRTC2 a...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ma, Huabin, Liu, Zeyuan, Zhong, Chuan-Qi, Liu, Yifei, Zhang, Zhirong, Liang, Yaoji, Li, Jingxian, Han, Shoufa, Han, Jiahuai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469919/
https://ncbi.nlm.nih.gov/pubmed/30782776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00554-18
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