Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells

MyoD inhibits cell proliferation and promotes muscle differentiation. A paradoxical feature of rhabdomyosarcoma (RMS), a tumor arising from muscle precursors, is the block of the differentiation program and the deregulated proliferation despite MyoD expression. A deficiency in RMS of a factor requir...

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Hauptverfasser: Puri, Pier Lorenzo, Wu, Zhenguo, Zhang, Peilin, Wood, Lauren D., Bhakta, Kunjan S., Han, Jiahuai, Feramisco, James R., Karin, Michael, Wang, Jean Y.J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2000
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316418/
https://ncbi.nlm.nih.gov/pubmed/10716945
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