Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells
MyoD inhibits cell proliferation and promotes muscle differentiation. A paradoxical feature of rhabdomyosarcoma (RMS), a tumor arising from muscle precursors, is the block of the differentiation program and the deregulated proliferation despite MyoD expression. A deficiency in RMS of a factor requir...
Uloženo v:
| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716945/ |
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