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Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells

MyoD inhibits cell proliferation and promotes muscle differentiation. A paradoxical feature of rhabdomyosarcoma (RMS), a tumor arising from muscle precursors, is the block of the differentiation program and the deregulated proliferation despite MyoD expression. A deficiency in RMS of a factor requir...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Puri, Pier Lorenzo, Wu, Zhenguo, Zhang, Peilin, Wood, Lauren D., Bhakta, Kunjan S., Han, Jiahuai, Feramisco, James R., Karin, Michael, Wang, Jean Y.J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316418/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716945/
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