Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells

MyoD inhibits cell proliferation and promotes muscle differentiation. A paradoxical feature of rhabdomyosarcoma (RMS), a tumor arising from muscle precursors, is the block of the differentiation program and the deregulated proliferation despite MyoD expression. A deficiency in RMS of a factor requir...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Genes Dev
Autori principali:	Puri, Pier Lorenzo, Wu, Zhenguo, Zhang, Peilin, Wood, Lauren D., Bhakta, Kunjan S., Han, Jiahuai, Feramisco, James R., Karin, Michael, Wang, Jean Y.J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2000
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716945/
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!