Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport

The p38 signal transduction pathway can be activated transiently or constitutively, depending on the contexts in which the activation occurs. However, the biological consequence of constitutive activation of p38 is largely unknown. After screening 300 transcriptional cofactors, we identified CRTC2 a...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Ma, Huabin, Liu, Zeyuan, Zhong, Chuan-Qi, Liu, Yifei, Zhang, Zhirong, Liang, Yaoji, Li, Jingxian, Han, Shoufa, Han, Jiahuai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469919/
https://ncbi.nlm.nih.gov/pubmed/30782776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00554-18
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