Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting

The vaccine elicitation of broadly neutralizing responses is a central goal of HIV research. Recently, we elicited cross-clade neutralizing responses against the N terminus of the fusion peptide (FP), a critical component of the HIV-entry machinery. While the consistency of the elicited cross-clade...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Cheng, Cheng, Xu, Kai, Kong, Rui, Chuang, Gwo-Yu, Corrigan, Angela R., Geng, Hui, Hill, Kurt R., Jafari, Alexander J., O’Dell, Sijy, Ou, Li, Rawi, Reda, Rowshan, Ariana P., Sarfo, Edward K., Sastry, Mallika, Saunders, Kevin O., Schmidt, Stephen D., Wang, Shuishu, Wu, Winston, Zhang, Baoshan, Doria-Rose, Nicole A., Haynes, Barton F., Scorpio, Diana G., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469787/
https://ncbi.nlm.nih.gov/pubmed/30995238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215163
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