Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting

The vaccine elicitation of broadly neutralizing responses is a central goal of HIV research. Recently, we elicited cross-clade neutralizing responses against the N terminus of the fusion peptide (FP), a critical component of the HIV-entry machinery. While the consistency of the elicited cross-clade...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cheng, Cheng, Xu, Kai, Kong, Rui, Chuang, Gwo-Yu, Corrigan, Angela R., Geng, Hui, Hill, Kurt R., Jafari, Alexander J., O’Dell, Sijy, Ou, Li, Rawi, Reda, Rowshan, Ariana P., Sarfo, Edward K., Sastry, Mallika, Saunders, Kevin O., Schmidt, Stephen D., Wang, Shuishu, Wu, Winston, Zhang, Baoshan, Doria-Rose, Nicole A., Haynes, Barton F., Scorpio, Diana G., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469787/
https://ncbi.nlm.nih.gov/pubmed/30995238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215163
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