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Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

The common conception of intrinsically disordered proteins (IDPs) is that they stochastically sample all possible configurations driven by thermal fluctuations. This is certainly true for many IDPs, which behave as swollen random coils that can be described using polymer models developed for homopol...

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Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: Choi, Ucheor B., Sanabria, Hugo, Smirnova, Tatyana, Bowen, Mark E., Weninger, Keith R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468417/
https://ncbi.nlm.nih.gov/pubmed/30909517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9030114
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